Primary Central Nervous System Lymphomas (PCNSL): MRI Response Criteria Revised

Overview

Journal Neurology

Specialty Neurology

Date 2005 Oct 12

PMID 16217075

Citations 15

Authors

W Kuker

T Nagele

E Thiel

M Weller

U Herrlinger

Affiliations

Soon will be listed here.

Abstract

The authors investigated the applicability of Macdonald response criteria to patients with primary CNS lymphoma (PCNSL). Four of 68 patients with persisting contrast-enhancing lesions after primary therapy did not receive further therapy, and none showed tumor progression after up to 54 months. Because contrast enhancement may not necessarily indicate residual, biologically active lymphoma, the authors propose a modification of the Macdonald response criteria.

Citing Articles

Patients with Primary Central Nervous System Lymphoma Not Eligible for Clinical Trials: Prognostic Factors, Treatment and Outcome.

Seidel S, Margold M, Kowalski T, Baraniskin A, Schroers R, Korfel A Cancers (Basel). 2021; 13(12).

PMID: 34208229 PMC: 8230869. DOI: 10.3390/cancers13122934.

Comparison of Measurement Techniques and Response Criteria for MR Imaging Follow-up in Adult Primary Central Nervous System Lymphoma.

Massicotte-Tisluck K, Vanderweyen D, Vendrell J, Fortin D, Gahide G AJNR Am J Neuroradiol. 2021; 42(8):1415-1420.

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Extent of radiological response does not reflect survival in primary central nervous system lymphoma.

van der Meulen M, Postma A, Smits M, Bakunina K, Minnema M, Seute T Neurooncol Adv. 2021; 3(1):vdab007.

PMID: 33615224 PMC: 7883767. DOI: 10.1093/noajnl/vdab007.

HDMTX-based induction therapy followed by consolidation with conventional systemic chemotherapy and intraventricular therapy (modified Bonn protocol) in primary CNS lymphoma: a monocentric retrospective analysis.

Seidel S, Korfel A, Kowalski T, Margold M, Ismail F, Schroers R Neurol Res Pract. 2020; 1:17.

PMID: 33324883 PMC: 7650117. DOI: 10.1186/s42466-019-0024-2.

HDMTX-based polychemotherapy including intraventricular therapy in elderly patients with primary CNS lymphoma: a single center series.

Seidel S, Kowalski T, Margold M, Baraniskin A, Schroers R, Martus P Ther Adv Neurol Disord. 2020; 13:1756286420951087.

PMID: 33101460 PMC: 7549157. DOI: 10.1177/1756286420951087.