Overactive Bladder
Overview
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The overactive bladder is a common condition, which has significant effects on quality of life. The aetiology in most cases is unknown, and treatment outcomes have until recently been unsatisfactory. Management includes excluding pathology and implementing behavioural changes such as caffeine reduction, bladder and pelvic floor training, as well as antimuscarinic drug therapy. Compliance is often problematic, and this can be improved with some of the newer antimuscarinics with fewer side-effects, and a good therapist/patient relationship. In the majority of cases this 'treatment package' is successful, but in those where it is not, intravesical therapies have been introduced, e.g. neuromodulation, alternative drug therapies (e.g. vanilloids, botox) and surgery. With a better understanding of the aetiology and identification of risk factors better outcomes from treatment are likely.
Clinical epidemiological insights into urinary incontinence.
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PMID: 28321473 DOI: 10.1007/s00192-017-3314-7.
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PMID: 27377948 PMC: 4932639. DOI: 10.5213/inj.1630464.232.
Effect of caffeine on bladder function in patients with overactive bladder symptoms.
Lohsiriwat S, Hirunsai M, Chaiyaprasithi B Urol Ann. 2011; 3(1):14-8.
PMID: 21346827 PMC: 3036994. DOI: 10.4103/0974-7796.75862.
Why do stress and urge incontinence co-occur much more often than expected?.
Minassian V, Stewart W, Hirsch A Int Urogynecol J Pelvic Floor Dysfunct. 2008; 19(10):1429-40.
PMID: 18528608 DOI: 10.1007/s00192-008-0647-2.