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Enhancement of Immune Responses to an HBV DNA Vaccine by Electroporation

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Journal Vaccine
Date 2005 Sep 6
PMID 16140436
Citations 36
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Abstract

These studies document the ability of electroporation (EP)-based DNA vaccination to induce multi-specific CTL responses to hepatitis B virus (HBV) DNA vaccination in normal mice and marked immune responses to multivalent HBV DNA immunization in larger animal species. These results suggest that electroporation-mediated HBV DNA vaccination is worth pursuing as a treatment for chronic HBV infection.

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