Lactate Concentration Gradient from Right Atrium to Pulmonary Artery: a Commentary

Overview

Journal Crit Care

Specialty Critical Care

Date 2005 Sep 3

PMID 16137378

Citations 1

Authors

Jacques Creteur

Affiliations

Soon will be listed here.

Abstract

Inadequate myocardial performance is a common complication of severe sepsis. Studies in humans strongly argue against a decrease in coronary blood flow in the pathogenesis of this sepsis-induced cardiac injury. Moreover, regional myocardial ischemia may well be present in sepsis patients with coexistent coronary artery disease. Nevertheless, the diagnosis of myocardial ischemia remains difficult in patients with sepsis, since elevation of troponin in these patients can be the result of a variety of conditions other than acute myocardial ischemia. The use of the right atrium to pulmonary artery lactate gradient could perhaps help the clinician in detecting myocardial ischemia in patients with sepsis.

Citing Articles

The concentration of oxygen, lactate and glucose in the central veins, right heart, and pulmonary artery: a study in patients with pulmonary hypertension.

Gutierrez G, Venbrux A, Ignacio E, Reiner J, Chawla L, Desai A Crit Care. 2007; 11(2):R44.

PMID: 17428338 PMC: 2206472. DOI: 10.1186/cc5739.

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