Influence of the Menstrual Cycle on the Sweating Response Measured by Direct Calorimetry in Women Exposed to Warm Environmental Conditions

Overview

Journal Eur J Appl Physiol Occup Physiol

Specialty Occupational Medicine

Date 1992 Jan 1

PMID 1612086

Citations 8

Authors

P Frascarolo

Y Schutz

E Jequier

Affiliations

Soon will be listed here.

Abstract

The whole body sweating response was measured at rest in eight women during the follicular (F) and the luteal (L) phases of the menstrual cycle. Subjects were exposed for 30-min to neutral (N) environmental conditions [ambient temperature (Ta) 28 degrees C] and then for 90-min to warm (W) environmental conditions (Ta, 35 degrees C) in a direct calorimeter. At the end of the N exposure, tympanic temperature (Tty) was 0.18 (SEM 0.06) degrees C higher in the L than in the F phase (P less than 0.05), whereas mean skin temperature (Tsk) was unchanged. During W exposure, the time to the onset of sweating as well as the concomitant increase in body heat content were similar in both phases. At the onset of sweating, the tympanic threshold temperature (Tty,thresh) was higher in the L phase [37.18 (SEM 0.08) degrees C] than in the F phase [36.95 (SEM 0.07) degrees C; P less than 0.01]. The magnitude of the shift in Tty,thresh [0.23 (SEM 0.07) degrees C] was similar to the L-F difference in Tty observed at the end of the N exposure. The mean skin threshold temperature was not statistically different between the two phases. The slope of the relationship between sweating rate and Tty was similar in F and L. It was concluded that the internal set point temperature of resting women exposed to warm environmental conditions shifted to a higher value during the L phase compared to the F phase of the menstrual cycle; and that the magnitude of the shift corresponded to the difference in internal temperature observed in neutral environmental conditions between the two phases.

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References

Jequier E, Felber J . Indirect calorimetry. Baillieres Clin Endocrinol Metab. 1987; 1(4):911-35. DOI: 10.1016/s0950-351x(87)80011-3. View

Spinnler G, Jequier E, Favre R, Dolivo M, VANNOTTI A . Human calorimeter with a new type of gradient layer. J Appl Physiol. 1973; 35(1):158-65. DOI: 10.1152/jappl.1973.35.1.158. View

Mitchell J, Nadel E, Stolwijk J . Respiratory weight losses during exercise. J Appl Physiol. 1972; 32(4):474-6. DOI: 10.1152/jappl.1972.32.4.474. View

Frye A, KAMON E, Webb M . Responses of menstrual women, amenorrheal women, and men to exercise in a hot, dry environment. Eur J Appl Physiol Occup Physiol. 1982; 48(2):279-88. DOI: 10.1007/BF00422988. View

Cannon J, Dinarello C . Increased plasma interleukin-1 activity in women after ovulation. Science. 1985; 227(4691):1247-9. DOI: 10.1126/science.3871966. View

Bittel J, HENANE R . Comparison of thermal exchanges in men and women under neutral and hot conditions. J Physiol. 1975; 250(3):475-89. PMC: 1348389. DOI: 10.1113/jphysiol.1975.sp011066. View

Cunningham D, Cabanac M . Evidence form behavioral thermoregulatory responses of a shift in setpoint temperature related to the menstrual cycle. J Physiol (Paris). 1971; 63(3):236-8. View

Hessemer V, Bruck K . Influence of menstrual cycle on shivering, skin blood flow, and sweating responses measured at night. J Appl Physiol (1985). 1985; 59(6):1902-10. DOI: 10.1152/jappl.1985.59.6.1902. View

Durnin J, Womersley J . Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr. 1974; 32(1):77-97. DOI: 10.1079/bjn19740060. View

10.

Bonjour J, WELTI H, Jequier E . [Calorimetric study of thermoregulatory mechanisms at the onset of sweating and during the menstrual cycle (author's transl)]. J Physiol (Paris). 1976; 72(2):181-204. View

11.

Kolka M, Stephenson L . Control of sweating during the human menstrual cycle. Eur J Appl Physiol Occup Physiol. 1989; 58(8):890-5. DOI: 10.1007/BF02332224. View

12.

Stephenson L, Kolka M . Menstrual cycle phase and time of day alter reference signal controlling arm blood flow and sweating. Am J Physiol. 1985; 249(2 Pt 2):R186-91. DOI: 10.1152/ajpregu.1985.249.2.R186. View

13.

Nakayama T, Suzuki M, Ishizuka N . Action of progesterone on preoptic thermosensitive neurones. Nature. 1975; 258(5530):80. DOI: 10.1038/258080a0. View

14.

Hessemer V, Bruck K . Influence of menstrual cycle on thermoregulatory, metabolic, and heart rate responses to exercise at night. J Appl Physiol (1985). 1985; 59(6):1911-7. DOI: 10.1152/jappl.1985.59.6.1911. View

15.

Wells C, Horvath S . Heat stress reponses related to the menstrual cycle. J Appl Physiol. 1973; 35(1):1-5. DOI: 10.1152/jappl.1973.35.1.1. View

16.

Frascarolo P, Schutz Y, Jequier E . Decreased thermal conductance during the luteal phase of the menstrual cycle in women. J Appl Physiol (1985). 1990; 69(6):2029-33. DOI: 10.1152/jappl.1990.69.6.2029. View