Mechanisms of Bronchial Hyperreactivity in Asthma and Chronic Obstructive Pulmonary Disease
Overview
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Bronchial hyperreactivity has long been recognized as a hallmark of chronic asthma. Less is known about the prevalence and mechanisms of hyperreactivity in chronic obstructive pulmonary disease (COPD). Currently, it is unclear whether the role and mechanisms of hyperreactivity are similar in patients with asthma and COPD or whether the underlying pathophysiologic abnormalities are different for both diseases. The aim of this review is to present an overview of current knowledge of the mechanisms of bronchial hyperreactivity in asthma and COPD.
Diagnostic differentiation between asthma and COPD in primary care using lung function testing.
Bouwens J, Bischoff E, In t Veen J, Schermer T NPJ Prim Care Respir Med. 2022; 32(1):32.
PMID: 36064807 PMC: 9445018. DOI: 10.1038/s41533-022-00298-4.
Su V, Ko S, Chang Y, Chou Y, Lee H, Yang K Allergy Asthma Immunol Res. 2022; 14(3):314-327.
PMID: 35557496 PMC: 9110917. DOI: 10.4168/aair.2022.14.3.314.
The Usefulness of FEF in Predicting Airway Hyperresponsiveness to Mannitol.
Kim Y, Lee H, Chung S, Yeo Y, Park T, Park D J Asthma Allergy. 2021; 14:1267-1275.
PMID: 34737579 PMC: 8560169. DOI: 10.2147/JAA.S318502.
Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5'-Nucleotidase (CD73).
Caiazzo E, Cerqua I, Riemma M, Turiello R, Ialenti A, Schrader J Front Pharmacol. 2020; 11:589343.
PMID: 33328996 PMC: 7734328. DOI: 10.3389/fphar.2020.589343.
ACO: Time to move from the description of different phenotypes to the treatable traits.
Toledo-Pons N, van Boven J, Roman-Rodriguez M, Perez N, Valera Felices J, Soriano J PLoS One. 2019; 14(1):e0210915.
PMID: 30677059 PMC: 6345463. DOI: 10.1371/journal.pone.0210915.