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Therapeutic Role of Mitoxantrone in Multiple Sclerosis

Overview
Journal Pharmacol Ther
Specialty Pharmacology
Date 2005 Aug 13
PMID 16095713
Citations 17
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Abstract

Mitoxantrone is approved by several health authorities for treatment of active forms of relapsing-remitting or secondary progressive multiple sclerosis (SPMS). This review provides an outline on relevant preclinical as well as clinical studies, places mitoxantrone in the context of other therapeutic approaches against multiple sclerosis (MS), and discusses relevant side effects. The current knowledge of the putative mechanisms of action of the compound is discussed.

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