Cockroach Allergens

Overview

Journal Curr Allergy Asthma Rep

Specialties Allergy & Immunology
Pulmonary Medicine

Date 2005 Aug 11

PMID 16091215

Citations 8

Authors

L Karla Arruda

Affiliations

Soon will be listed here.

Abstract

Cockroaches produce several potent allergens associated with sensitization and the development of asthma. Many of these allergens have been cloned and produced as biologically active recombinant proteins. Three-dimensional structure and molecular modeling, in addition to studies on the biological functions of these proteins in the cockroach, have provided new insights into the ability of these allergens to cause immunoglobulin E antibody responses. Recent studies have pointed to a potential role of recombinant cockroach allergens for diagnosis and the development of novel therapeutic strategies that may benefit cockroach-allergic patients.

Citing Articles

Spatial distribution of histamine in bed bug-infested homes.

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Expression profiles of an inactive aspartic protease (Bla g 2 allergen) in different tissues and developmental stages of the German cockroach (Blattella germanica).

Rodriques A, Myers A, Scharf M, Aryal U, Bennett G, Gondhalekar A Arch Insect Biochem Physiol. 2022; 111(2):e21918.

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Cockroach exposure and perceived stress interact to predict clinical outcomes in childhood asthma.

Rabito F, Werthmann D, He H, Madkour A, Arroyave W, Sever M BMC Pulm Med. 2021; 21(1):83.

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Resistance development characteristics of reared German cockroach (Blattodea: Blattellidae) to chlorpyrifos.

Hou W, Xin J, Lu H Sci Rep. 2021; 11(1):3505.

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The cockroach and allergic diseases.

Sohn M, Kim K Allergy Asthma Immunol Res. 2012; 4(5):264-9.

PMID: 22950031 PMC: 3423599. DOI: 10.4168/aair.2012.4.5.264.

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