Age-specific Antibody to Hepatitis E Virus Has Remained Constant During the Past 20 Years in Japan

Overview

Journal J Viral Hepat

Specialty Gastroenterology

Date 2005 Jun 30

PMID 15985017

Citations 10

Authors

E Tanaka

A Matsumoto

N Takeda

T-C Li

T Umemura

K Yoshizawa

Y Miyakawa

T Miyamura

K Kiyosawa

Affiliations

Soon will be listed here.

Abstract

We investigated the presence of antibodies to hepatitis E virus (anti-HEV) and hepatitis A virus (anti-HAV) by enzyme immunoassays in sera from 1015 individuals collected in 1974, 1984 and 1994. Age-specific profiles of anti-HEV remained unchanged with a peak at 40-49 years, while those of anti-HAV started to increase in individuals aged 20-29 years in 1974, 30-39 years in 1984 and 40-49 years in 1994. These results suggest that a silent HEV infection has been taking place in the last 20 years or so in Japan, while HAV infection has been terminated at least since 1974.

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