» Articles » PMID: 15949867

Antibiotic Resistance-the Problem Intensifies

Overview
Specialty Pharmacology
Date 2005 Jun 14
PMID 15949867
Citations 43
Authors
Affiliations
Soon will be listed here.
Abstract

While previously recognized antibiotic-resistant bacteria continue to increase in frequency and numbers globally, new resistance problems have recently emerged which further complicate and impede treatment of critical infectious diseases. Vancomycin resistance among Staphylococcus aureus, extended spectrum beta-lactamases among gram-negative pathogens, and fluoroquinolone resistance among already multidrug-resistant Escherichia coli and Neisseria gonorrheae are adding to the toll of resistance on patients suffering with infectious diseases.

Citing Articles

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review.

Muteeb G, Rehman M, Shahwan M, Aatif M Pharmaceuticals (Basel). 2023; 16(11).

PMID: 38004480 PMC: 10675245. DOI: 10.3390/ph16111615.


Hit 'em Where It Hurts: Gram-Negative Bacterial Lipopolysaccharide as a Vaccine Target.

Cross A Microbiol Mol Biol Rev. 2023; 87(3):e0004522.

PMID: 37432116 PMC: 10521362. DOI: 10.1128/mmbr.00045-22.


Ferulic acid derivatives inhibiting tetK and MsrA efflux pumps.

Pinheiro P, Santiago G, Freitas da Silva F, Araujo A, de Oliveira C, Freitas P Biotechnol Rep (Amst). 2022; 34:e00717.

PMID: 35284249 PMC: 8914127. DOI: 10.1016/j.btre.2022.e00717.


On-chip label-free impedance-based detection of antibiotic permeation.

Kaur J, Ghorbanpoor H, Ozturk Y, Kaygusuz O, Avci H, Darcan C IET Nanobiotechnol. 2021; 15(1):100-106.

PMID: 34694729 PMC: 8675796. DOI: 10.1049/nbt2.12019.


Design, Synthesis and Biological Evaluation of Biphenylglyoxamide-Based Small Molecular Antimicrobial Peptide Mimics as Antibacterial Agents.

Yu T, Kuppusamy R, Yasir M, Hassan M, Alghalayini A, Gadde S Int J Mol Sci. 2020; 21(18).

PMID: 32947921 PMC: 7555970. DOI: 10.3390/ijms21186789.