Hemicerebellectomy Blocks the Enhancement of Cortical Motor Output Associated with Repetitive Somatosensory Stimulation in the Rat

Overview

Journal J Physiol

Specialty Physiology

Date 2005 Jun 11

PMID 15946961

Citations 22

Authors

Nordeyn Oulad Ben Taib

Oulad Ben Taib Nordeyn

Mario Manto

Manto Mario

Massimo Pandolfo

Pandolfo Massimo

Jacques Brotchi

Brotchi Jacques

Affiliations

Soon will be listed here.

Abstract

Repetitive peripheral stimulation is associated with an enhancement of the intensity of corticomotor responses. We analysed the effects of hemicerebellectomy on the modulation of cortical motor output associated with repetitive electrical stimulation of the sciatic nerve in the rat. Hemicerebellectomy blocked the enhancement of the corticomotor response. The cerebellum is a key player in this form of short-term plasticity.

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References

Devor A . The great gate: control of sensory information flow to the cerebellum. Cerebellum. 2003; 1(1):27-34. DOI: 10.1080/147342202753203069. View

Bantli H, Bloedel J . The action of the dentate nucleus on the excitability of spinal motoneurons via pathways which do not involve the primary sensorimotor cortex. Brain Res. 1975; 88(1):86-90. DOI: 10.1016/0006-8993(75)90952-x. View

Sanes J, Donoghue J . Plasticity and primary motor cortex. Annu Rev Neurosci. 2000; 23:393-415. DOI: 10.1146/annurev.neuro.23.1.393. View

Gozariu M, Roth V, Keime F, LE Bars D, Willer J . An electrophysiological investigation into the monosynaptic H-reflex in the rat. Brain Res. 1998; 782(1-2):343-7. DOI: 10.1016/s0006-8993(97)01402-9. View

DAgata V, Drago F, Serapide F, Cicirata F . Effects of cerebellectomy on motivation-related behavior: a time-course study. Physiol Behav. 1993; 53(1):173-6. DOI: 10.1016/0031-9384(93)90027-d. View

Nixon P . The role of the cerebellum in preparing responses to predictable sensory events. Cerebellum. 2003; 2(2):114-22. DOI: 10.1080/14734220309410. View

Tarnecki R . Responses of the red nucleus neurons to limb stimulation after cerebellar lesions. Cerebellum. 2003; 2(2):96-100. DOI: 10.1080/14734220309405. View

Courville J . Somatotopical organization of the projection from the nucleus interpositus anterior of the cerebellum to the red nucleus. An experimental study in the cat with silver impregnation methods. Exp Brain Res. 1966; 2(3):191-215. DOI: 10.1007/BF00236713. View

Florenzano F, Viscomi M, Cavaliere F, Volonte C, Molinari M . Cerebellar lesion up-regulates P2X1 and P2X2 purinergic receptors in precerebellar nuclei. Neuroscience. 2002; 115(2):425-34. DOI: 10.1016/s0306-4522(02)00397-4. View

10.

Roland P, Eriksson L, Widen L, Stone-Elander S . Changes in Regional Cerebral Oxidative Metabolism Induced by Tactile Learning and Recognition in Man. Eur J Neurosci. 1989; 1(1):3-18. DOI: 10.1111/j.1460-9568.1989.tb00769.x. View

11.

Tesche C, Karhu J . Anticipatory cerebellar responses during somatosensory omission in man. Hum Brain Mapp. 2000; 9(3):119-42. PMC: 6871963. View

12.

Werk C, Chapman C . Long-term potentiation of polysynaptic responses in layer V of the sensorimotor cortex induced by theta-patterned tetanization in the awake rat. Cereb Cortex. 2003; 13(5):500-7. DOI: 10.1093/cercor/13.5.500. View

13.

Di Lazzaro V, Restuccia D, Nardone R, Leggio M, Oliviero A, Profice P . Motor cortex changes in a patient with hemicerebellectomy. Electroencephalogr Clin Neurophysiol. 1995; 97(5):259-63. DOI: 10.1016/0013-4694(95)00110-k. View

14.

Fox J, HITCHCOCK E . Changes in F wave size during dentatotomy. J Neurol Neurosurg Psychiatry. 1982; 45(12):1165-7. PMC: 491706. DOI: 10.1136/jnnp.45.12.1165. View

15.

Mackel R . The role of the monkey sensory cortex in the recovery from cerebellar injury. Exp Brain Res. 1987; 66(3):638-52. DOI: 10.1007/BF00270696. View

16.

Johansson K, Lindgren I, Widner H, Wiklund I, Johansson B . Can sensory stimulation improve the functional outcome in stroke patients?. Neurology. 1993; 43(11):2189-92. DOI: 10.1212/wnl.43.11.2189. View

17.

Drozdowski W . F wave in acute cerebellar damage. Acta Neurol Scand. 1995; 91(2):141-4. DOI: 10.1111/j.1600-0404.1995.tb00421.x. View

18.

Taib N, Manto M, Laute M, Brotchi J . The cerebellum modulates rodent cortical motor output after repetitive somatosensory stimulation. Neurosurgery. 2005; 56(4):811-20. DOI: 10.1227/01.neu.0000156616.94446.00. View

19.

Sasaki K, Gemba H . Plasticity of cortical function related to voluntary movement motor learning and compensation following brain dysfunction. Acta Neurochir Suppl (Wien). 1987; 41:18-28. DOI: 10.1007/978-3-7091-8945-0_4. View

20.

Rosenfield M, Moore J . Red nucleus lesions disrupt the classically conditioned nictitating membrane response in rabbits. Behav Brain Res. 1983; 10(2-3):393-8. DOI: 10.1016/0166-4328(83)90043-8. View