Hyponatremia Associated with Repeated Use of Levetiracetam

Overview

Journal Epilepsia

Specialty Neurology

Date 2005 Jun 11

PMID 15946344

Citations 8

Authors

Khalil Nasrallah

Brian Silver

Affiliations

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Abstract

Levetiracetam (LEV) is increasingly used as adjunctive anticonvulsant therapy because of apparent low toxicity. Somnolence, asthenia, headache, dizziness, and nervousness are the most frequently reported side effects (1). We describe a patient, predisposed to the development of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), in whom hyponatremia developed after two challenges of LEV.

Citing Articles

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Incidence trends and risk factors for hyponatremia in epilepsy patients: A large-scale real-world data study.

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Recurrent Hyponatremia: Levetiracetam - An Uncommon Cause.

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A case of cerebral salt wasting syndrome in a patient with central diabetes insipidus and status epilepticus.

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Three cases in which drug-induced hyponatremia was improved by replacing carbamazepine with lacosamide.

Morimoto M, Suzaki I, Shimakawa S, Hashimoto T, Nakatsu T, Hamada S Clin Case Rep. 2020; 8(7):1166-1170.

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