Patellamide E: a New Cyclic Peptide from the Ascidian Lissoclinum Patella

Overview

Journal J Nat Prod

Date 1992 Mar 1

PMID 1593285

Citations 14

Authors

L A McDonald

C M Ireland

Affiliations

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Abstract

A new cyclic peptide, patellamide E [1], was isolated from the ascidian Lissoclinum patella collected at Pulau Salu, Singapore. Its structure was determined by nmr spectroscopy, and its absolute configuration by acid hydrolysis and analysis of the derivatized constituent amino acids by hplc. Patellamide E was mildly cytotoxic against human colon tumor cells in vitro.

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