Fallacies of Preoperative Lymphoscintigraphy in Detecting Sentinel Node in Breast Cancer

Overview

Journal World J Surg Oncol

Publisher Biomed Central

Specialties General Surgery
Oncology

Date 2005 Jun 2

PMID 15927059

Citations 5

Authors

Manoj Pandey

Surya Vs Deo

R Maharajan

Affiliations

Soon will be listed here.

Abstract

BACKGROUND: Preoperative lymphoscintigraphy is one of the three methods of evaluating sentinel nodes in patients with breast cancer; however, it has been reported to have a high false negative rate. CASE PRESENTATIONS: We report here two cases where the preoperative lymphoscintigraphy was found to be fallacious. A 44-year-old female with T2N0 breast cancer underwent preoperative lymphoscintigraphy with Tc99 sulfur colloid which failed to show any uptake in axilla or internal mammary chain. Intraoperative scintigraphy with blue dye and hand held gamma probe identified sentinel lymph node in axilla. Another patient with T2N0 lesion underwent preoperative lymphoscintigraphy which showed a sentinel lymph node in axilla and another in supraclevicular fossa. Intraoperative scintigraphy failed to show supraclevicular node however axillary node was correctly identified. CONCLUSION: These two cases further strengthen the need to carry out triple test in identification of sentinel lymph node in patients with breast cancer. It also demonstrates the fallacies of preoperative lymphoscintigraphy.

Citing Articles

Effects of the number of removed lymph nodes on survival outcome in patients with sentinel node-negative breast cancer.

Cipolla C, Galvano A, Vieni S, Saputo F, Lupo S, Latteri M World J Surg Oncol. 2021; 19(1):306.

PMID: 34666764 PMC: 8524859. DOI: 10.1186/s12957-021-02418-9.

Nonvisualization of sentinel node by lymphoscintigraphy in advanced breast cancer.

Wosnitzer B, Mirtcheva R, Ghesani M Radiol Case Rep. 2016; 5(3):444.

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Preoperative Scintigrams to Identify the Sentinel Lymph Node in Breast Cancer: a Waste of Time?.

Sharma N, Pinto A, Notghi A, Sintler M Indian J Surg. 2016; 77(Suppl 3):1480-3.

PMID: 27011606 PMC: 4775584. DOI: 10.1007/s12262-013-0994-1.

Lymphoscintigraphy and triangulated body marking for morbidity reduction during sentinel node biopsy in breast cancer.

Krynyckyi B, Shafir M, Kim S, Kim D, Travis A, Moadel R Int Semin Surg Oncol. 2005; 2:25.

PMID: 16277655 PMC: 1308847. DOI: 10.1186/1477-7800-2-25.

Preoperative lymphoscintigraphy and triangulated patient body marking are important parts of the sentinel node process in breast cancer.

Krynyckyi B, Kim S, Kim C World J Surg Oncol. 2005; 3:56.

PMID: 16120218 PMC: 1215530. DOI: 10.1186/1477-7819-3-56.

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