Allostatic Load: a Mechanism of Socioeconomic Health Disparities?

Overview

Journal Biol Res Nurs

Specialties Biology
Nursing

Date 2005 May 28

PMID 15919999

Citations 77

Authors

Sarah L Szanton

Jessica M Gill

Jerilyn K Allen

Affiliations

Soon will be listed here.

Abstract

Although research on health disparities has been prioritized by the National Institutes of Health, the Institute of Medicine, and Healthy People 2010, little has been published that examines the biology underlying health disparities. Allostatic load is a multisystem construct theorized to quantify stress-induced biological risk. Differences in allostatic load may reflect differences in stress exposure and thus provide a mechanistic link to understanding health disparities. The purpose of this systematic review is to examine the construct of allostatic load and the published studies that employ it in an effort to understand whether the construct can be useful in quantifying health disparities. The published literature demonstrates that allostatic load is elevated in those of low socioeconomic status (SES) as compared to those of high SES. The reviewed articles vary in the justification for inclusion of variables. Recommendations for future research are made in the contexts of measurement, methodology, and racial composition of participants.

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