Trisomy 8 As the Sole Cytogenetic Abnormality in a Case of Extraskeletal Mesenchymal Chondrosarcoma

Overview

Journal Cancer Genet Cytogenet

Date 2005 May 19

PMID 15899388

Citations 6

Authors

Ken M Gatter

Susan Olson

Helen Lawce

Anne E Rader

Affiliations

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Abstract

Mesenchymal chondrosarcoma is a rare malignant tumor that comprises about 3-10% of all sarcomas. Reports of cytogenetic studies of mesenchymal chondrosarcoma are limited and no consistent cytogenetic abnormality has surfaced. Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. We report what to our knowledge is the first case of trisomy 8 as the sole cytogenetic abnormality in a mesenchymal chondrosarcoma.

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