Photoprotective Activity of Buddleja Scordioides

Overview

Journal Fitoterapia

Publisher Elsevier

Specialties Pharmacology
Rehabilitation Medicine

Date 2005 May 14

PMID 15890460

Citations 9

Authors

J G Avila Acevedo

C M C Castaneda

F J C Benitez

D A Duran

V R Barroso

C G Martinez

L J L Munoz

C A Martinez

A Romo de Vivar

Affiliations

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Abstract

The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement.

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