Successful Treatment of Multiple Pseudallescheria Boydii Brain Abscesses and Ventriculitis/ependymitis in a 2-year-old Child After a Near-drowning Episode

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 2005 May 3

PMID 15864705

Citations 19

Authors

Kay Mursch

Svorad Trnovec

Heinrich Ratz

Detlef Hammer

Regine Horre

Albrecht Klinghammer

Sybren de Hoog

Julianne Behnke-Mursch

Affiliations

Soon will be listed here.

Abstract

Rationale: We report on a cerebral infection by Pseudallescheria boydii in a 21-month-old boy after a near-drowning episode. MRI revealed multiple (> 60) intracerebral abscesses.

Methods: The surgical therapy included CSF drainage and microsurgical resection of one abscess for microbiological diagnosis. Antimycotic therapy included terbinafine and intraventricular caspofungin in addition to voriconazole.

Results: Systemic side effects of chemotherapy were not observed. After placement of a ventriculoperitoneal shunt, the boy was transferred to a rehabilitation clinic and improved neurologically. After 20 months, MRI documented a continuing remission of the disease.

Conclusion: Our case proves that an aggressive treatment should be undertaken and can be successful in CNS pseudallescheriasis.

Citing Articles

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