» Articles » PMID: 15862110

Hydrogels for Pharmaceutical and Biomedical Applications

Overview
Publisher Begell House
Specialty Pharmacology
Date 2005 May 3
PMID 15862110
Citations 48
Authors
Affiliations
Soon will be listed here.
Abstract

Hydrogels are crosslinked hydrophilic polymer structures that can imbibe large amounts of water or biological fluids. Hydrogels are one of the upcoming classes of polymer-based systems that embrace numerous biomedical and pharmaceutical applications. This review discusses various parameters of hydrogels such as surface properties, water content and swelling behavior, effect of nature of polymer, ionic content, and thermodynamics, all of which can influence the biomedical usage of hydrogels. Meanwhile, intelligent or environment-sensitive hydrogels and bioadhesive hydrogels continue to be important materials for medical applications; therefore, a part of this review is devoted to some of their important classes. Hydrogels are extensively used for various biomedical applications--tissue engineering, molecular imprinting, wound dressings materials, immunoisolation, drug delivery, etc. Thus, this review aims to throw light on the numerous applications that hydrogels have in the biomedical arena.

Citing Articles

Gels as Promising Delivery Systems: Physicochemical Property Characterization and Recent Applications.

Wang E, Qi Z, Cao Y, Li R, Wu J, Tang R Pharmaceutics. 2025; 17(2).

PMID: 40006616 PMC: 11858892. DOI: 10.3390/pharmaceutics17020249.


Establishment of Optimal Drug Delivery System and Evaluation of Utilization of Hydrogel Contact Lens According to the Addition Method of Tretinoin and Bovine Serum Albumin.

Park H, Sung A Polymers (Basel). 2025; 17(2).

PMID: 39861232 PMC: 11768321. DOI: 10.3390/polym17020159.


Evaluation of physical and chemical modifications to drug reservoirs for stimuli-responsive microneedles.

Li L, Anjani Q, Hutton A, Li M, Sabri A, Vora L Drug Deliv Transl Res. 2024; .

PMID: 39565514 DOI: 10.1007/s13346-024-01737-0.


Harmonizing Innovations: An In-Depth Comparative Review on the Formulation, Applications, and Future Perspectives of Aerogels and Hydrogels in Pharmaceutical Sciences.

Alaghawani N, Alkhatib H, Elmancy L, Daou A Gels. 2024; 10(10).

PMID: 39451316 PMC: 11507152. DOI: 10.3390/gels10100663.


Effect of Silk Fibroin on the Mechanical and Transport Properties of Agarose Hydrogels.

Richterova V, Pekar M Gels. 2024; 10(10).

PMID: 39451265 PMC: 11508024. DOI: 10.3390/gels10100611.