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West Nile Virus Meningitis in a Chronic Immunosuppressed Patient with Rheumatoid Arthritis

Overview
Journal Clin Rheumatol
Publisher Springer
Specialty Rheumatology
Date 2005 Apr 28
PMID 15856365
Citations 4
Authors
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Abstract

The clinical presentation of West Nile virus (WNV) can be severe in immunosuppressed patients. A 65-year-old with steroid-dependent rheumatoid arthritis on infliximab and methotrexate presented with meningitis and profound muscular weakness. Serum WNV IgM and IgG antibody were positive. WNV should be included in the differential diagnosis of neurological symptoms in peak months.

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References
1.
Feinstein S, Akov Y, Lachmi B, Lehrer S, RANNON L, Katz D . Determination of human IgG and IgM class antibodies to West Nile virus by enzyme linked immunosorbent assay (ELISA). J Med Virol. 1985; 17(1):63-72. DOI: 10.1002/jmv.1890170110. View

2.
. Update: Investigations of West Nile virus infections in recipients of organ transplantation and blood transfusion--Michigan, 2002. MMWR Morb Mortal Wkly Rep. 2002; 51(39):879. View

3.
Nash D, Mostashari F, Fine A, Miller J, OLeary D, Murray K . The outbreak of West Nile virus infection in the New York City area in 1999. N Engl J Med. 2001; 344(24):1807-14. DOI: 10.1056/NEJM200106143442401. View

4.
Diamond M, Shrestha B, Marri A, Mahan D, Engle M . B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus. J Virol. 2003; 77(4):2578-86. PMC: 141119. DOI: 10.1128/jvi.77.4.2578-2586.2003. View

5.
Giladi M, Martin D, Siegman-Igra Y, Korczyn A, Rosso R, Berger S . West Nile encephalitis in Israel, 1999: the New York connection. Emerg Infect Dis. 2001; 7(4):659-61. PMC: 2631756. DOI: 10.3201/eid0704.010410. View