Use of PCR to Diagnose Toxoplasma Gondii Chorioretinitis in Eyes with Severe Vitritis

Overview

Journal Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2005 Apr 6

PMID 15807829

Citations 4

Authors

Narciss Okhravi

Colin D Jones

Nora Carroll

Peter Adamson

Philip Luthert

Susan Lightman

Affiliations

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Abstract

Two cases are reported of intraocular inflammation in which severe vitritis hampered the fundal view, making an accurate clinical diagnosis impossible, and vitreous analysis using conventional techniques was unhelpful. PCR for Toxoplasma gondii was positive in both cases and provided the only way of confirming the diagnosis. Other ocular samples also underwent PCR for Toxoplasma DNA and the specificity of this approach is demonstrated.

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