[Oral Treatment with Tretinoin: Andrological, Trichological, Ophthalmological Findings and Effects on Acne (author's Transl)]

Overview

Journal Arch Dermatol Res

Specialty Dermatology

Date 1979 May 29

PMID 157723

Citations 1

Authors

G Plewig

W B Schill

C Hofmann

Affiliations

Soon will be listed here.

Abstract

Twelve patients (20 +/- 2 years) with acne vulgaris were treated orally with 20-30 mg/day tretinoin (vitamin A acid) over 90-300 days. Various laboratory tests were performed to rule out unwanted pharmacological side effects. Tretinoin therapy was well tolerated except for minor complaints of dryness around the mucous membranes of mouth and nose. The acne remained unchanged. All laboratory tests were unremarkable except for a significant rise of ejaculate volume. Other sperm parameters, trichological, ophthalmological as well as blood and urine analyses showed no measurable effects of tretinoin therapy.

Citing Articles

Acne vulgaris: pathogenesis and treatment.

Cunliffe W Br Med J. 1980; 280(6229):1394-6.

PMID: 6448651 PMC: 1601712. DOI: 10.1136/bmj.280.6229.1394.

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