Serum Haemolytic Complement Levels in German Dahlem Red Chickens Are Affected by Three Major Genes (naked Neck, Dwarf, Frizzled) of Tropical Interest

Overview

Journal Trop Anim Health Prod

Publisher Springer

Specialties Tropical Medicine
Veterinary Medicine

Date 2005 Feb 26

PMID 15729892

Citations 2

Authors

P Dorny

R Baelmans

H K Parmentier

M G B Nieuwland

F Demey

D Berkvens

Affiliations

Soon will be listed here.

Abstract

German Dahlem Red chickens with three different major genes of tropical interest: Nana- (naked neck), Ff- (frizzled) and dw- (dwarf), respectively, were tested for serum haemolytic complement, which is essential in innate host defence against infectious agents. Eight different combinations of genes for body size and feather coverage were evaluated. Significant differences both for both the calcium-dependent (classical, CPW) and the calcium-independent (alternative, APW) complement titres were found between the phenotypes. Phenotype nanaffDw- showed the highest complement status. The frizzled (Ff-) gene had a negative influence on APW titres, whereas the dwarf (dw-) gene had a negative influence on CPW titres. The naked neck (Nana-) gene had various influences on the haemolytic complement status. All tested hens had MHC (B) 21 haplotypes, whereas the gene for dwarfism appeared to be linked with the B19 haplotype. It was concluded that introducing major genes (Nana-, dw-, Ff-) to conquer environmental stress in hot climates can have a negative impact on certain aspects of the innate immunity of poultry.

Citing Articles

Differential expression of Toll-like receptor mRNA in White Leghorn and indigenous chicken of India.

Ramasamy K, Reddy M, Raveendranathan D, Murugesan S, Chatterjee R, Ullengala R Vet Res Commun. 2010; 34(7):633-9.

PMID: 20668934 DOI: 10.1007/s11259-010-9431-0.

Haemolytic complement activity and humoral immune responses to sheep red blood cells in indigenous chickens and in eight German Dahlem Red chicken lines with different combinations of major genes (dwarf, naked neck and frizzled) of tropical interest.

Baelmans R, Parmentier H, Nieuwland M, Dorny P, Demey F, Berkvens D Trop Anim Health Prod. 2005; 37(3):173-86.

PMID: 15747855 DOI: 10.1023/b:trop.0000049274.28640.d7.

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