Stereocontrolled Synthesis of Angularly Substituted 1-azabicyclic Rings by Cationic 2-aza-cope Rearrangements

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2005 Feb 25

PMID 15727473

Citations 6

Authors

Zachary D Aron

Larry E Overman

Affiliations

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Abstract

A new synthesis of 1-azabicyclic molecules having angular substitution is reported. This method can be employed to prepare a range of 1-azabicylic rings, including ones containing vicinal quaternary carbon centers and three contiguous stereocenters. [structure: see text]

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