Effects of Propolis on Blood Glucose, Blood Lipid and Free Radicals in Rats with Diabetes Mellitus

Overview

Journal Pharmacol Res

Publisher Elsevier

Specialty Pharmacology

Date 2005 Jan 5

PMID 15629260

Citations 60

Authors

H U Fuliang

H R Hepburn

Hongzhuan Xuan

Minli Chen

S Daya

S E Radloff

Affiliations

Soon will be listed here.

Abstract

The effects of ethanol (EEP) and water (WSD) extracts of propolis collected from north China on blood glucose, blood lipid and free radicals in rats with diabetes mellitus were studied. The results show that EEP and WSD led to decreased levels of blood glucose (FBG), fructosamine (FRU), malonaldehyde (MDA), nitric oxide (NO), nitric oxide synthetase (NOS), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C) in serum of fasting rats; and to increased serum levels of high-density lipoprotein cholesterol (HDL-C) and superoxide dismutase (SOD). This suggests that propolis can control blood glucose and modulate the metabolism of glucose and blood lipid, leading to decreased outputs of lipid peroxidation and scavenge the free radicals in rats with diabetes mellitus.

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