Primary Cutaneous Plasmacytoma After Rejection of a Transplanted Kidney: Case Report and Review of the Literature

Overview

Journal Int J Hematol

Specialty Hematology

Date 2004 Dec 24

PMID 15615262

Citations 3

Authors

Gianpaolo Tessari

Fabio Fabbian

Chiara Colato

Fabio Benedetti

Massimo Franchini

Vittorio Ortalda

Lucia Cavallini

Annalisa Barba

Affiliations

Soon will be listed here.

Abstract

Immunosuppressed organ allograft recipients are at risk of developing lymphomas and lymphoproliferative disorders as a consequence of immunosuppressive therapy and long-term antigenic stimulation from both the graft and possible viral infections. No more than 4% of the malignant tumors detected in organ recipients are plasmacytomas. Primary cutaneous plasmacytoma is a rare type of cutaneous B-cell lymphoma arising primarily in the skin. It is derived from clonally expanded plasma cells with various degrees of maturation and atypia. We report the occurrence of a solitary cutaneous plasmacytoma in a 56-year-old male patient undergoing hemodialysis after rejection of a grafted kidney. The diagnosis was made a few months after the kidney had been surgically removed. A thorough examination showed no evidence of systemic disease. Skin lesions were successfully treated with local radiotherapy. After 2 years of follow-up there were no local or systemic recurrences.

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