Risk Factors and Obstetric Complications Associated with Macrosomia

Overview

Journal Int J Gynaecol Obstet

Publisher Wiley

Specialty Gynecology & Obstetrics

Date 2004 Nov 19

PMID 15548393

Citations 67

Authors

N E Stotland

A B Caughey

E M Breed

G J Escobar

Affiliations

Soon will be listed here.

Abstract

Objective: Macrosomia is associated with adverse maternal outcomes. The objective of this study was to characterize the epidemiology of macrosomia and related maternal complications.

Method: Live births (146,526) were identified between 1995 and 1999 in the Kaiser Permanente Medical Care Program's Northern California Region (KPMCP NCR) database. Bivariate and multivariate analyses were performed for risk factors and complications associated with macrosomia (birth weight >4500 g).

Result: Male infant sex, multiparity, maternal age 30-40, white race, diabetes, and gestational age >41 weeks were associated with macrosomia (p<0.001). In bivariate and multivariate analyses, macrosomia was associated with higher rates of cesarean birth, chorioamnionitis, shoulder dystocia, fourth-degree perineal lacerations, postpartum hemorrhage, and prolonged hospital stay (p<0.01).

Conclusion: Macrosomia was associated with adverse maternal outcomes in this cohort. More research is needed to determine how to prevent complications related to excessive birth weight.

Citing Articles

Early Prediction of Fetal Macrosomia Through Maternal Lipid Profiles.

Chagovets V, Frankevich N, Starodubtseva N, Tokareva A, Derbentseva E, Yuryev S Int J Mol Sci. 2025; 26(3).

PMID: 39940917 PMC: 11818448. DOI: 10.3390/ijms26031149.

Exploring the Father's Role in Determining Neonatal Birth Weight: A Narrative Review.

Libretti A, Savasta F, Nicosia A, Corsini C, De Pedrini A, Leo L Medicina (Kaunas). 2024; 60(10).

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Predictors of Postpartum Hemorrhage and Associated Outcomes at a Midwest Academic Medical Center.

Mooberry M, Voss N, Wendt L, Kenne K, Jackson J, Rysavy M Womens Health Rep (New Rochelle). 2024; 5(1):358-366.

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The CHANGED Score-A New Tool for the Prediction of Insulin Dependency in Gestational Diabetes.

Rostin P, Balke S, Sroka D, Fangmann L, Weid P, Henrich W J Clin Med. 2023; 12(22).

PMID: 38002781 PMC: 10672469. DOI: 10.3390/jcm12227169.

The Incidence and Management of Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus.

Ikoh Rph C, Tang Tinong R Cureus. 2023; 15(8):e44468.

PMID: 37664380 PMC: 10471197. DOI: 10.7759/cureus.44468.