Synthesis of Primary Amines by the Electrophilic Amination of Grignard Reagents with 1,3-dioxolan-2-one O-sulfonyloxime

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2004 Nov 19

PMID 15548090

Citations 6

Authors

Mitsuru Kitamura

Takahiro Suga

Shunsuke Chiba

Koichi Narasaka

Affiliations

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Abstract

Primary amines are prepared by the electrophilic amination of Grignard reagents with 4,4,5,5-tetramethyl-1,3-dioxolan-2-one O-phenylsulfonyloxime and the acidic hydrolysis of the resulting imines. [reaction: see text]

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