Rod Outer Segments Are Designed for Optimum Photon Detection

Overview

Journal Biol Cybern

Specialties Neurology
Physiology

Date 1992 Jan 11

PMID 1550880

Authors

K N LEIBOVIC

Affiliations

Soon will be listed here.

Abstract

The proposal that rod outer segment length is optimal with respect to photon absorption and noise control is extended and tested in a number of species. We find good agreement with our optimality criterion in duplex retinae where rods act as detectors of one or a few photons, but not in all rod retinae nor in those which are exposed to significant photic environmental noise.

References

Baylor D, Nunn B . Electrical properties of the light-sensitive conductance of rods of the salamander Ambystoma tigrinum. J Physiol. 1986; 371:115-45. PMC: 1192713. DOI: 10.1113/jphysiol.1986.sp015964. View

Cornwall M, Ripps H, Chappell R, Jones G . Membrane current responses of skate photoreceptors. J Gen Physiol. 1989; 94(4):633-47. PMC: 2228967. DOI: 10.1085/jgp.94.4.633. View

LEIBOVIC K . Some conjectures on the design of a rod outer segment. Biol Cybern. 1990; 63(5):359-61. DOI: 10.1007/BF00202752. View

Nakatani K, Tamura T, Yau K . Light adaptation in retinal rods of the rabbit and two other nonprimate mammals. J Gen Physiol. 1991; 97(3):413-35. PMC: 2216483. DOI: 10.1085/jgp.97.3.413. View

Baylor D, Lamb T, Yau K . Responses of retinal rods to single photons. J Physiol. 1979; 288:613-34. PMC: 1281447. View

Attwell D, Borges S, Wu S, Wilson M . Signal clipping by the rod output synapse. Nature. 1987; 328(6130):522-4. DOI: 10.1038/328522a0. View

Baylor D, Lamb T, Yau K . The membrane current of single rod outer segments. J Physiol. 1979; 288:589-611. PMC: 1281446. View

Baylor D, Nunn B, Schnapf J . The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis. J Physiol. 1984; 357:575-607. PMC: 1193276. DOI: 10.1113/jphysiol.1984.sp015518. View

Bader C, Macleish P, Schwartz E . A voltage-clamp study of the light response in solitary rods of the tiger salamander. J Physiol. 1979; 296:1-26. PMC: 1279061. DOI: 10.1113/jphysiol.1979.sp012988. View

10.

Matthews G . Spread of the light response along the rod outer segment: an estimate from patch-clamp recordings. Vision Res. 1986; 26(4):535-41. DOI: 10.1016/0042-6989(86)90002-7. View

11.

HAGINS W, Penn R, Yoshikami S . Dark current and photocurrent in retinal rods. Biophys J. 1970; 10(5):380-412. PMC: 1367773. DOI: 10.1016/S0006-3495(70)86308-1. View

12.

ALPERN M, Pugh Jr E . The density and photosensitivity of human rhodopsin in the living retina. J Physiol. 1974; 237(2):341-70. PMC: 1350887. DOI: 10.1113/jphysiol.1974.sp010485. View

13.

Cornwall M, Fein A, Macnichol Jr E . Spatial localization of bleaching adaptation in isolated vertebrate rod photoreceptors. Proc Natl Acad Sci U S A. 1983; 80(9):2785-8. PMC: 393913. DOI: 10.1073/pnas.80.9.2785. View

14.

Baylor D, Matthews G, Yau K . Two components of electrical dark noise in toad retinal rod outer segments. J Physiol. 1980; 309:591-621. PMC: 1274605. DOI: 10.1113/jphysiol.1980.sp013529. View

15.

Rosenkranz J . New aspects of the ultrastructure of frog rod outer segments. Int Rev Cytol. 1977; 50:25-158. DOI: 10.1016/s0074-7696(08)60098-4. View

16.

Bodoia R, Detwiler P . Patch-clamp recordings of the light-sensitive dark noise in retinal rods from the lizard and frog. J Physiol. 1985; 367:183-216. PMC: 1193059. DOI: 10.1113/jphysiol.1985.sp015820. View

17.

Lamb T, McNaughton P, Yau K . Spatial spread of activation and background desensitization in toad rod outer segments. J Physiol. 1981; 319:463-96. PMC: 1243851. DOI: 10.1113/jphysiol.1981.sp013921. View

18.

Attwell D, Wilson M . Behaviour of the rod network in the tiger salamander retina mediated by membrane properties of individual rods. J Physiol. 1980; 309:287-315. PMC: 1274585. DOI: 10.1113/jphysiol.1980.sp013509. View

19.

Harosi F . Absorption spectra and linear dichroism of some amphibian photoreceptors. J Gen Physiol. 1975; 66(3):357-82. PMC: 2226208. DOI: 10.1085/jgp.66.3.357. View