Metabolic Aspects of Low Carbohydrate Diets and Exercise
Overview
Authors
Affiliations
Following a low carbohydrate diet, there is a shift towards more fat and less carbohydrate oxidation to provide energy to skeletal muscle, both at rest and during exercise. This review summarizes recent work on human skeletal muscle carbohydrate and fat metabolic adaptations to a low carbohydrate diet, focusing mainly on pyruvate dehydrogenase and pyruvate dehydrogenase kinase, and how these changes relate to the capacity for carbohydrate oxidation during exercise.
Soto-Mota A, Jansen L, Norwitz N, Pereira M, Ebbeling C, Ludwig D J Nutr. 2023; 154(4):1080-1086.
PMID: 38128881 PMC: 11347797. DOI: 10.1016/j.tjnut.2023.12.017.
Pilis K, Pilis A, Stec K, Pilis W, Langfort J, Letkiewicz S Nutrients. 2018; 10(12).
PMID: 30518095 PMC: 6317154. DOI: 10.3390/nu10121914.
Effects of a 4-Week Very Low-Carbohydrate Diet on High-Intensity Interval Training Responses.
Cipryan L, Plews D, Ferretti A, Maffetone P, Laursen P J Sports Sci Med. 2018; 17(2):259-268.
PMID: 29769827 PMC: 5950743.
Selection and Characterization of Palmitic Acid Responsive Patients with an OXPHOS Complex I Defect.
Theunissen T, Gerards M, Hellebrekers D, van Tienen F, Kamps R, Sallevelt S Front Mol Neurosci. 2017; 10:336.
PMID: 29093663 PMC: 5651253. DOI: 10.3389/fnmol.2017.00336.
Zinn C, Wood M, Williden M, Chatterton S, Maunder E J Int Soc Sports Nutr. 2017; 14:22.
PMID: 28706467 PMC: 5506682. DOI: 10.1186/s12970-017-0180-0.