The BOLD Response: a New Look at an Old Riddle

Overview

Journal Neuroreport

Specialty Neurology

Date 2004 Oct 16

PMID 15486470

Citations 4

Authors

Valentine L Marcar

Thomas Loenneker

Affiliations

Soon will be listed here.

Abstract

Functional imaging has struggled for two decades to establish a quantitative link between the neuronal activity and the change in signal obtained. This review proposes a division of neuronal activity into a component relating to the electrical discharge activity and a component relating to the size of the activated neuronal population. These two components are argued to have opposing influences on the BOLD signal. The influence of these two components on the BOLD signal, are summarised in the standard model.

Citing Articles

Effects of contact with a dog on prefrontal brain activity: A controlled trial.

Marti R, Petignat M, Marcar V, Hattendorf J, Wolf M, Hund-Georgiadis M PLoS One. 2022; 17(10):e0274833.

PMID: 36197880 PMC: 9534402. DOI: 10.1371/journal.pone.0274833.

AGING-ASSOCIATED COGNITIVE DECLINE IS REVERSED BY D-SERINE SUPPLEMENTATION.

Nava-Gomez L, Calero-Vargas I, Higinio-Rodriguez F, Vazquez-Prieto B, Olivares-Moreno R, Ortiz-Retana J eNeuro. 2022; .

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Absolute pitch--functional evidence of speech-relevant auditory acuity.

Oechslin M, Meyer M, Jancke L Cereb Cortex. 2009; 20(2):447-55.

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How depth of anesthesia influences the blood oxygenation level-dependent signal from the visual cortex of children.

Marcar V, Schwarz U, Martin E, Loenneker T AJNR Am J Neuroradiol. 2006; 27(4):799-805.

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