[Tissue Engineering of the Urinary Bladder]

Overview

Journal Urologe A

Specialty Urology

Date 2004 Sep 29

PMID 15452694

Citations 1

Authors

G Ram-Liebig

O W Hakenberg

M P Wirth

Affiliations

Soon will be listed here.

Abstract

In tissue engineering of the urinary bladder with autologous cell transplantation, high differentiation of the cells cultivated in vitro on biocompatible membranes is essential for the functionality of the tissue constructs after implantation. The terminal differentiation of superficial urothelial cells has a key role because of the barrier function of these cells against urine. The aim of this study was to determine optimized conditions for the creation of terminally differentiated urothelium to cover large membrane surfaces. This can bring us closer to the goal of using functioning tissue constructs in clinical trials.

Citing Articles

[Reconstructive urology in transition. From its origin into the all too near future].

Sievert K, Seibold J, Schultheiss D, Feil G, Sperling H, Fisch M Urologe A. 2006; 45 Suppl 4:52-8.

PMID: 16933123 DOI: 10.1007/s00120-006-1153-0.

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