[Transpupillary Thermotherapy for Subfoveal Choroidal Neovascularization. A 9-month Follow-up]
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Purpose: The purpose of this study was to evaluate the efficiency, stability, and safety of transpupillary thermotherapy as a treatment of subfoveal occult choroidal neovascularizations (CNV) in age-related macular degeneration.
Methods: Transpupillary thermotherapy (TTT) was performed in 40 patients with uni- or bilateral predominantly occult CNV. Laser light derived from an infrared diode laser at 810 nm was used to apply spots for a duration of 60 s. A complete ophthalmic examination was performed prior to and 9 months after the treatment.
Results: After 9 months, visual acuity remained stable in 65% (+/-2 lines). In 35% of the patients TTT could not prevent further visual loss. Retinal leakage, assessed by fluorescein angiography, stabilized in 67.5% of the treated patients.
Conclusions: The present data show stabilization of visual acuity in 65% after TTT. Compared to the natural course of occult and mixed subfoveal CNV, these data give some evidence for patient benefit after TTT.
Scholl H, Fleckenstein M, Krohne T, Holz F Ophthalmologe. 2005; 102(12):1152-61.
PMID: 16283184 DOI: 10.1007/s00347-005-1293-4.