Assignment of the Human Renal Dipeptidase Gene (DPEP1) to Band Q24 of Chromosome 16

Overview

Journal Cytogenet Cell Genet

Publisher Karger

Specialty Genetics

Date 1992 Jan 1

PMID 1544318

Citations 21

Authors

H Nakagawa

J Inazawa

K Inoue

S Misawa

K Kashima

H Adachi

H Nakazato

T Abe

Affiliations

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Abstract

Renal dipeptidase (DPEP1) or dehydropeptidase-I (E.C.3.4.13.11) is a kidney membrane enzyme which hydrolyzes a variety of dipeptides. DPEP1 is implicated in the renal metabolism of glutathione and its conjugates and is also responsible for hydrolysis of beta-lactam antibiotics. Using a human DPEP1 cDNA probe, we mapped the human renal dipeptidase gene to human chromosome 16 at band q24 by in situ hybridization.

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