Long Polar Fimbriae Contribute to Colonization by Escherichia Coli O157:H7 in Vivo

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 2004 Sep 24

PMID 15385526

Citations 47

Authors

Dianna M Jordan

Nancy Cornick

Alfredo G Torres

Evelyn A Dean-Nystrom

James B Kaper

Harley W Moon

Affiliations

Soon will be listed here.

Abstract

The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.

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