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Development of a Polymer Stent with Shape Memory Effect As a Drug Delivery System

Overview
Journal J Mater Sci Mater Med
Publisher Springer
Specialty Biomedical Engineering
Date 2004 Sep 7
PMID 15348481
Citations 22
Authors
H M Wache
D J Tartakowska
A Hentrich
M H Wagner
Affiliations
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Abstract

The article presents a new concept for vascular endoprothesis (stent). Almost all commercially available stents are made of metallic materials. A common after effect of stent implantation is restenosis. Several studies on metal stents coated with drug show, that the use of a drug delivery system may reduce restenosis. The purpose of this work is to develop a new stent for the drug delivery application. The shape memory properties of thermoplastic polyurethane allow to design a new fully polymeric self-expandable stent. The possibility to use the stent as a drug delivery system is described.

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Simple and Efficient Synthesis of Oligoetherdiamines: Hardeners of Epoxyurethane Oligomers for Obtaining Coatings with Shape Memory Effect.

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Screening of the Supercritical Impregnation of Leaves Extract into Filaments of Thermoplastic Polyurethane (TPU) and Polylactic Acid (PLA) Intended for Biomedical Applications.

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