Treatment of Lichen Planopilaris with Mycophenolate Mofetil
Overview
Authors
Affiliations
Mycophenolate mofetil (MMF) is an immunosuppressive drug that has recently been used to treat autoimmune and inflammatory skin diseases. We report the first case of lichen planopilaris (LPP) successfully treated with MMF. The treatment of our patient demonstrates a novel therapeutic option for patients with LPP; MMF treatment may be preferable to azathioprine treatment because MMF has a safer adverse-effect profile. Larger studies must be performed to establish the risk-benefit ratio of various therapeutic dosages of MMF for these patients.
Fatemi F, Esfahanian F, Asilian A, Mohaghegh F, Saber M Dermatol Res Pract. 2022; 2022:3792489.
PMID: 36254319 PMC: 9569223. DOI: 10.1155/2022/3792489.
Therapeutic management of classic lichen planopilaris: a systematic review.
Errichetti E, Figini M, Croatto M, Stinco G Clin Cosmet Investig Dermatol. 2018; 11:91-102.
PMID: 29520159 PMC: 5833781. DOI: 10.2147/CCID.S137870.
Fatemi Naeini F, Saber M, Asilian A, Hosseini S Int J Prev Med. 2017; 8:37.
PMID: 28584619 PMC: 5450502. DOI: 10.4103/ijpvm.IJPVM_156_17.
Tremezaygues L, Vogt T, Muller C Hautarzt. 2011; 63(5):411-4.
PMID: 21971770 DOI: 10.1007/s00105-011-2242-6.
Alopecia: evaluation and treatment.
Gordon K, Tosti A Clin Cosmet Investig Dermatol. 2011; 4:101-6.
PMID: 21833160 PMC: 3149477. DOI: 10.2147/CCID.S10182.