Lymphangioleiomyomatosis

Overview

Journal Clin Chest Med

Specialty Pulmonary Medicine

Date 2004 Aug 28

PMID 15331193

Citations 14

Authors

Marilyn K Glassberg

Affiliations

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Abstract

Lymphangioleiomyomatosis (LAM) is a rare idiopathic disease predominately affecting women. The disease is characterized by peribronchial, perivascular, and perilymphatic proliferation of smooth muscle like cells resulting in vascular and airway obstruction and cyst formation. The natural history of pulmonary LAM is unknown, and it displays remarkable diversity in its clinical course. More than 400 citations are currently listed in the literature for LAM. This article reviews and updates the rapidly expanding knowledge about LAM.

Citing Articles

Small airways morphological alterations associated with functional impairment in lymphangioleiomyomatosis.

Mendonca L, de Souza Xavier Costa N, Nascimento E, Oliveira M, de Carvalho C, Baldi B BMC Pulm Med. 2024; 24(1):22.

PMID: 38195527 PMC: 10777584. DOI: 10.1186/s12890-023-02837-2.

A 34-Year-Old Woman from Brazil with Pulmonary Lymphangioleiomyomatosis Diagnosed by Raised Serum Vascular Endothelial Growth Factor-D (VEGF-D) Levels and Lung Cysts on Computed Tomography Imaging Presenting with COVID-19 Pneumonia.

Carneiro A, Mafort T, Lopes A Am J Case Rep. 2021; 22:e932660.

PMID: 34330886 PMC: 8340921. DOI: 10.12659/AJCR.932660.

Concentration of Serum Vascular Endothelial Growth Factor (VEGF-D) and Its Correlation with Functional and Clinical Parameters in Patients with Lymphangioleiomyomatosis from a Brazilian Reference Center.

Amaral A, Oliveira M, Meira Dias O, Arimura F, Freitas C, Acencio M Lung. 2019; 197(2):139-146.

PMID: 30623243 DOI: 10.1007/s00408-018-00191-3.

Use of sirolimus in the treatment of lymphangioleiomyomatosis: favorable responses in patients with different extrapulmonary manifestations.

Freitas C, Baldi B, Araujo M, Heiden G, Kairalla R, Carvalho C J Bras Pneumol. 2015; 41(3):275-80.

PMID: 26176526 PMC: 4541764. DOI: 10.1590/S1806-37132015000004553.

Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis--a clinicoradiological diagnosis.

Gupta K, Goyal A, Saggar K, Banerjee A Pan Afr Med J. 2015; 20:207.

PMID: 26113938 PMC: 4470415. DOI: 10.11604/pamj.2015.20.207.5490.