The Retroviral RNA Dimer Linkage: Different Structures May Reflect Different Roles

Overview

Journal Retrovirology

Publisher Biomed Central

Specialty Microbiology

Date 2004 Aug 20

PMID 15317659

Citations 41

Authors

Jane Greatorex

Affiliations

Soon will be listed here.

Abstract

Retroviruses are unique among virus families in having dimeric genomes. The RNA sequences and structures that link the two RNA molecules vary, and these differences provide clues as to the role of this feature in the viral lifecycles. This review draws upon examples from different retroviral families. Differences and similarities in both secondary and tertiary structure are discussed. The implication of varying roles for the dimer linkage in related viruses is considered.

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