» Articles » PMID: 15289513

Further Ethical and Social Issues in Using a Cocaine Vaccine: Response to Hall and Carter

Overview
Journal J Med Ethics
Specialty Medical Ethics
Date 2004 Aug 4
PMID 15289513
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Evaluation of the potential of a cocaine vaccine requires a detailed understanding of the intended and unintended social consequences of its use. Prospective technology assessment is always difficult, but in the case of treatment and prevention of cocaine addiction we need to understand not only the neuroscience and pharmacology of cocaine addiction, but also social attitudes to drug use and addiction, the social context of drug use, and the factors which make drug use a rational strategy for an addict and make treatment seeking or relapse more or less likely. By considering different scenarios related to differing levels of effectiveness of the vaccine, the authors argue that vaccination will be at best a useful adjunct to existing methods of treatment, rather than a substitute for them.

Citing Articles

Pharmacy stakeholder reports on ethical and logistical considerations in anti-opioid vaccine development.

Wartenweiler V, Chung G, Stewart A, Wenthur C BMC Med Ethics. 2021; 22(1):30.

PMID: 33766021 PMC: 7992836. DOI: 10.1186/s12910-021-00599-2.


Ethical Implications in Vaccine Pharmacotherapy for Treatment and Prevention of Drug of Abuse Dependence.

Carfora A, Cassandro P, Feola A, La Sala F, Petrella R, Borriello R J Bioeth Inq. 2018; 15(1):45-55.

PMID: 29350320 DOI: 10.1007/s11673-017-9834-5.


Immune to addiction: the ethical dimensions of vaccines against substance abuse.

Young M, Sisti D, Rimon-Greenspan H, Schwartz J, Caplan A Nat Immunol. 2012; 13(6):521-4.

PMID: 22610239 DOI: 10.1038/ni.2321.

References
1.
Hasman A, Holm S . Nicotine conjugate vaccine: is there a right to a smoking future?. J Med Ethics. 2004; 30(4):344-5. PMC: 1733882. DOI: 10.1136/jme.2002.001602. View

2.
Hall W, Carter L . Ethical issues in using a cocaine vaccine to treat and prevent cocaine abuse and dependence. J Med Ethics. 2004; 30(4):337-40. PMC: 1733917. DOI: 10.1136/jme.2003.004739. View

3.
Uhl G . Are over-simplified views of addiction neuroscience providing too simplified ethical considerations?. Addiction. 2003; 98(7):872-3. DOI: 10.1046/j.1360-0443.2003.00453.x. View

4.
Hall W, Carter L, Morley K . Addiction, ethics and scientific freedom. Addiction. 2003; 98(7):873-4. DOI: 10.1046/j.1360-0443.2003.00457.x. View

5.
Kosten T, Biegel D . Therapeutic vaccines for substance dependence. Expert Rev Vaccines. 2003; 1(3):363-71. DOI: 10.1586/14760584.1.3.365. View