The Therapeutic Potential of Melatonin: a Review of the Science

Overview

Journal MedGenMed

Specialty General Medicine

Date 2004 Jul 22

PMID 15266271

Citations 34

Authors

Samir Malhotra

Girish Sawhney

Promila Pandhi

Affiliations

Soon will be listed here.

Citing Articles

Administration of melatonin nanoparticles improves testicular blood flow, echotexture of testicular parenchyma, scrotal circumference, and levels of estradiol and nitric oxide in prepubertal ossimi rams under summer heat stress.

Fayez E, Samir H, Youssef F, Salama A, ElSayed M Vet Res Commun. 2024; 48(6):3953-3965.

PMID: 39441486 PMC: 11538174. DOI: 10.1007/s11259-024-10563-1.

The Role of Water-Soluble Vitamins and Vitamin D in Prevention and Treatment of Depression and Seasonal Affective Disorder in Adults.

Jahan-Mihan A, Stevens P, Medero-Alfonso S, Brace G, Overby L, Berg K Nutrients. 2024; 16(12).

PMID: 38931257 PMC: 11206829. DOI: 10.3390/nu16121902.

The Relationship between Circadian Rhythm and Cancer Disease.

Munteanu C, Turti S, Achim L, Muresan R, Souca M, Prifti E Int J Mol Sci. 2024; 25(11).

PMID: 38892035 PMC: 11172077. DOI: 10.3390/ijms25115846.

Efficacy of melatonin in alleviating disorders arising from repeated exposure to sevoflurane in males and females of the Wistar rats during preadolescence.

Heydari F, Nasiri M, Haroabadi A, Fahanik Babaei J, Pestehei S Sci Rep. 2024; 14(1):11889.

PMID: 38789558 PMC: 11126601. DOI: 10.1038/s41598-024-62170-4.

Melatonin Administration Enhances Testicular Volume, Testicular Blood Flow, Semen Parameters and Antioxidant Status during the Non-Breeding Season in Bafra Rams.

Akar M, Cevik M, Kocaman A, Kaya C, Esin B, Bjorkman S Animals (Basel). 2024; 14(3).

PMID: 38338085 PMC: 10854573. DOI: 10.3390/ani14030442.

References

Herxheimer A, Petrie K . Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev. 2002; (2):CD001520. DOI: 10.1002/14651858.CD001520. View

Nordlund J, LERNER A . The effects of oral melatonin on skin color and on the release of pituitary hormones. J Clin Endocrinol Metab. 1977; 45(4):768-74. DOI: 10.1210/jcem-45-4-768. View

Wetterberg L . The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions. Psychoneuroendocrinology. 1983; 8(1):75-80. DOI: 10.1016/0306-4530(83)90042-2. View

Lissoni P, Vigore L, Rescaldani R, ROVELLI F, Brivio F, Giani L . Neuroimmunotherapy with low-dose subcutaneous interleukin-2 plus melatonin in AIDS patients with CD4 cell number below 200/mm3: a biological phase-II study. J Biol Regul Homeost Agents. 1995; 9(4):155-8. View

Reiter R . The ageing pineal gland and its physiological consequences. Bioessays. 1992; 14(3):169-75. DOI: 10.1002/bies.950140307. View

Brown R, Kocsis J, Caroff S, Amsterdam J, Winokur A, Stokes P . Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects. Am J Psychiatry. 1985; 142(7):811-6. DOI: 10.1176/ajp.142.7.811. View

Bubenik G . Localization, physiological significance and possible clinical implication of gastrointestinal melatonin. Biol Signals Recept. 2001; 10(6):350-66. DOI: 10.1159/000046903. View

Maestroni G, Conti A . Beta-endorphin and dynorphin mimic the circadian immunoenhancing and anti-stress effects of melatonin. Int J Immunopharmacol. 1989; 11(4):333-40. DOI: 10.1016/0192-0561(89)90078-7. View

Juszczak M, Stempniak B . Melatonin inhibits the substance P-induced secretion of vasopressin and oxytocin from the rat hypothalamo-neurohypophysial system: in vitro studies. Brain Res Bull. 2003; 59(5):393-7. DOI: 10.1016/s0361-9230(02)00942-5. View

10.

Parlakpinar H, Sahna E, Ozer M, Ozugurlu F, Vardi N, Acet A . Physiological and pharmacological concentrations of melatonin protect against cisplatin-induced acute renal injury. J Pineal Res. 2002; 33(3):161-6. DOI: 10.1034/j.1600-079x.2002.02910.x. View

11.

Silman R . Melatonin: a contraceptive for the nineties. Eur J Obstet Gynecol Reprod Biol. 1993; 49(1-2):3-9. DOI: 10.1016/0028-2243(93)90099-x. View

12.

Dahlitz M, Alvarez B, Vignau J, English J, Arendt J, Parkes J . Delayed sleep phase syndrome response to melatonin. Lancet. 1991; 337(8750):1121-4. DOI: 10.1016/0140-6736(91)92787-3. View

13.

Antolin I, Mayo J, Sainz R, del Brio M, Herrera F, Martin V . Protective effect of melatonin in a chronic experimental model of Parkinson's disease. Brain Res. 2002; 943(2):163-73. DOI: 10.1016/s0006-8993(02)02551-9. View

14.

Skwarlo-Sonta K . Melatonin in immunity: comparative aspects. Neuro Endocrinol Lett. 2002; 23 Suppl 1:61-6. View

15.

Roy A, Virkkunen M, Linnoila M . Reduced central serotonin turnover in a subgroup of alcoholics?. Prog Neuropsychopharmacol Biol Psychiatry. 1987; 11(2-3):173-7. DOI: 10.1016/0278-5846(87)90056-x. View

16.

Barchas J, DACOSTA F, Spector S . Acute pharmacology of melatonin. Nature. 1967; 214(5091):919-20. DOI: 10.1038/214919a0. View

17.

Sack R, Lewy A . Desmethylimipramine treatment increases melatonin production in humans. Biol Psychiatry. 1986; 21(4):406-10. DOI: 10.1016/0006-3223(86)90171-x. View

18.

Roy A, Virkkunen M, Guthrie S, Linnoila M . Indices of serotonin and glucose metabolism in violent offenders, arsonists, and alcoholics. Ann N Y Acad Sci. 1986; 487:202-20. DOI: 10.1111/j.1749-6632.1986.tb27900.x. View

19.

Mori W, Aoyama H, Mori N . Melatonin protects rats from injurious effects of a glucocorticoid, dexamethasone. Jpn J Exp Med. 1984; 54(6):255-61. View

20.

Lieberman H, Garfield G, Waldhauser F, Lynch H, Wurtman R . Possible behavioral consequences of light-induced changes in melatonin availability. Ann N Y Acad Sci. 1985; 453:242-52. DOI: 10.1111/j.1749-6632.1985.tb11814.x. View