Adaptation of Cardiac Myocyte Contractile Properties to Exercise Training

Overview

Journal Exerc Sport Sci Rev

Specialty Orthopedics

Date 2004 Jul 10

PMID 15243207

Citations 11

Authors

Gary M Diffee

Affiliations

Soon will be listed here.

Abstract

Recent work suggests that chronic exercise induces alterations in the contractile properties of cardiac myocytes. These alterations include increased sensitivity to activation by Ca, changes in the force-length relationship, and increased power output. A recently observed shift in expression of myosin light chain 1 subunit isoforms induced by training may provide a molecular mechanism for these contractile alterations.

Citing Articles

Electrically stimulated in vitro heart cell mimic of acute exercise reveals novel immediate cellular responses to exercise: Reduced contractility and metabolism, but maintained calcium cycling and increased myofilament calcium sensitivity.

Da Silva Costa A, Ghouri I, Johnston A, McGlynn K, McNair A, Bowman P Cell Biochem Funct. 2023; 41(8):1147-1161.

PMID: 37665041 PMC: 10947300. DOI: 10.1002/cbf.3847.

A high-whey-protein diet does not enhance mechanical and structural remodeling of cardiac muscle in response to aerobic exercise in rats.

Boldt K, Joumaa V, Turnbull J, Fedak P, Herzog W Phys Act Nutr. 2022; 26(1):28-38.

PMID: 35510443 PMC: 9081358. DOI: 10.20463/pan.2022.0005.

Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart.

Kellermayer D, Kiss B, Tordai H, Olah A, Granzier H, Merkely B Int J Mol Sci. 2021; 22(20).

PMID: 34681770 PMC: 8537917. DOI: 10.3390/ijms222011110.

Molecular Mechanisms Mediating Adaptation to Exercise.

Gholamnezhad Z, Megarbane B, Rezaee R Adv Exp Med Biol. 2020; 1228:45-61.

PMID: 32342449 DOI: 10.1007/978-981-15-1792-1_3.

Force properties of skinned cardiac muscle following increasing volumes of aerobic exercise in rats.

Boldt K, Rios J, Joumaa V, Herzog W J Appl Physiol (1985). 2018; 125(2):495-503.

PMID: 29722623 PMC: 6139514. DOI: 10.1152/japplphysiol.00631.2017.