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Age-related Changes in Ocular and Corneal Aberrations

Overview
Journal Am J Ophthalmol
Specialty Ophthalmology
Date 2004 Jul 6
PMID 15234298
Citations 32
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Abstract

Purpose: To compare the ocular and corneal higher-order aberrations (HA) in eyes of different ages.

Design: Observational cross-sectional study.

Methods: Sixty-six eyes of 66 normal subjects (age range 4-69 years; average 37.4 +/- 15.4 years) were examined. Wavefront aberrations of the whole eye (ocular) and cornea were measured for the central 4 mm using a Hartmann-Shack aberrometer.

Results: Ocular Coma-like aberration (r = 0.270, P =.029), Spherical-like aberration (r = 0.531, P =.001), and total HA(r = 0.431, P =.001) were significantly correlated with age, whereas the corneal aberrations were not significantly correlated. The ocular total HA aberrations increased significantly after age 50 years.

Conclusions: After 50 years of age, ocular aberrations increased abruptly due to the increase of lenticular HA. Customized ablation should be carefully considered, especially in eyes of presbyopic age.

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