Performance Evaluation of the Positron Scanner ECAT EXACT
Overview
Affiliations
The Cologne Special is a prototype of the ECAT EXACT (model 921), a new generation of Siemens-CTI PET scanners. It consists of three rings of 48 BGO block detectors each, covering an axial field of view of 16.2 cm with a patient port of 56.2 cm diameter. This results in a total of 24 rings with 384 crystals each, giving 47 contiguous image planes in two-dimensional (2D) mode. Total system sensitivity is 216 kcps/microCi/ml for a 20 cm cylinder phantom in 2D. This increases to 1.5 Mcps/microCi/ml in 3D. Data are acquired in the stationary mode only (no wobble motion), resulting in a transaxial spatial resolution of better than 6 mm full width at half-maximum (FWHM) at the center, which degrades to 7.5 mm tangentially and 9.6 mm radially at a radius of 20 cm. Average axial resolution changes from 5.0 mm FWHM at the center to 8.1 mm at R = 20 cm. Count rate performance was investigated at different low energy discriminator settings and found to be linear up to 2.5 microCi/ml with a 20 cm phantom. The magnitude and distribution of scatter were evaluated for both septa-extended and septa-retracted conditions for a range of energy thresholds. Brain, heart, and whole-body studies with the new tomograph demonstrate the versatility of its applications without compromising on physical performance.
Becker-Bense S, Buchholz H, Baier B, Schreckenberger M, Bartenstein P, Zwergal A PLoS One. 2016; 11(11):e0165935.
PMID: 27824897 PMC: 5100888. DOI: 10.1371/journal.pone.0165935.
Bismuth germanate coupled to near ultraviolet silicon photomultipliers for time-of-flight PET.
Kwon S, Gola A, Ferri A, Piemonte C, Cherry S Phys Med Biol. 2016; 61(18):L38-L47.
PMID: 27589153 PMC: 5056849. DOI: 10.1088/0031-9155/61/18/L38.
Reduced D2/D3 Receptor Binding of Extrastriatal and Striatal Regions in Temporal Lobe Epilepsy.
Bernedo Paredes V, Buchholz H, Gartenschlager M, Breimhorst M, Schreckenberger M, Werhahn K PLoS One. 2015; 10(11):e0141098.
PMID: 26544593 PMC: 4636381. DOI: 10.1371/journal.pone.0141098.
Quantification of dopamine transporter density with [18F]FECNT PET in healthy humans.
Nye J, Votaw J, Douglas Bremner J, Davis M, Voll R, Camp V Nucl Med Biol. 2014; 41(3):217-22.
PMID: 24533985 PMC: 4657438. DOI: 10.1016/j.nucmedbio.2013.12.013.
Ventral and dorsal streams processing visual motion perception (FDG-PET study).
Becker-Bense S, Buchholz H, Eulenburg P, Best C, Bartenstein P, Schreckenberger M BMC Neurosci. 2012; 13:81.
PMID: 22800430 PMC: 3467181. DOI: 10.1186/1471-2202-13-81.