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Mollaret's Meningitis Caused by Herpes Simplex Virus Type 2: Case Report and Literature Review

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Publisher Springer
Date 2004 Jun 29
PMID 15221615
Citations 5
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Abstract

Presented here is a new case of benign recurrent aseptic meningitis, or Mollaret's meningitis, in which cerebrospinal fluid was positive for herpes simplex virus type 2 using the polymerase chain reaction test. A search of the existing medical literature revealed 58 previously reported cases of Mollaret's meningitis in which samples of cerebrospinal fluid were tested for herpes simplex virus. Discussed here are the history, clinical and laboratory findings, differential diagnoses and therapeutic options for this illness.

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References
1.
Bergstrom T, Vahlne A, ALESTIG K, Jeansson S, Forsgren M, LYCKE E . Primary and recurrent herpes simplex virus type 2-induced meningitis. J Infect Dis. 1990; 162(2):322-30. DOI: 10.1093/infdis/162.2.322. View

2.
Steel J, Dix R, Baringer J . Isolation of herpes simplex virus type 1 in recurrent (Mollaret's) meningitis. Trans Am Neurol Assoc. 1981; 106:37-42. View

3.
Stamm A, Livingston W, Cobbs C, Dismukes W . Failure of colchicine in the treatment of Mollaret's meningitis. Arch Intern Med. 1984; 144(11):2265-6. View

4.
Gignoux L, Ryvlin P, Najioullah F, Mauguiere F . [Recurrent Mollaret's meningitis of herpetic origin]. Presse Med. 1998; 27(29):1470-2. View

5.
Lee C, Chao C, Yu K, Liu C . Mollaret's meningitis: a case report and literature review. Zhonghua Yi Xue Za Zhi (Taipei). 1992; 49(4):289-93. View