Spontaneous Pneumothorax Developed in Patients with Bronchiolitis Obliterans After Unrelated Hematopoietic Stem Cell Transplantation: Case Report and Review of the Literature

Overview

Journal Int J Hematol

Specialty Hematology

Date 2004 Jun 1

PMID 15168602

Citations 3

Authors

Ho-Jin Shin

Chi Young Park

Yun Hee Park

Yoo Jin Kim

Chang-Ki Min

Seok Lee

Dong-Wook Kim

Jong Wook Lee

Woo Sung Min

Chun Choo Kim

Affiliations

Soon will be listed here.

Abstract

Spontaneous pneumothorax following unrelated hematopoietic stem cell transplantation developed in our 2 patients with bronchiolitis obliterans. Bronchiolitis obliterans is a form of obstructive airway disease and is considered a manifestation of chronic graft-versus-host disease (GVHD). Both of the patients were the recipients of marrow from HLA-matched unrelated donors after a preparative regimen with total body irradiation. Chronic GVHD after transplantation is a common feature in these cases. In contrast to other patients with pneumothorax described in the literature, our patients did not develop bullae. We describe a pneumothorax secondary to bronchiolitis obliterans that complicated the posttransplantation course.

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