Trypanocidal Activity of Chemical Constituents from Lychnophora Salicifolia Mart

Overview

Journal Phytother Res

Publisher Wiley

Date 2004 May 27

PMID 15162371

Citations 7

Authors

Christiane Oliveira Jordao

Walter Vichnewski

Gloria Emilia Petto de Souza

Sergio Albuquerque

Joao Luis Callegari Lopes

Affiliations

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Abstract

The ethyl acetate extract from leaves plus inflorescences of L. salicifolia showed significant trypanocidal activity against trypomastigote forms of T. cruzi, which was due to the flavonoid quercetin-7,3',4'-trimethyl ether and the sesquiterpenoid lychnopholic acid. Despite the use of some species of Lychnophora in folk medicine for pain relief, crude extracts from L. salicifolia Mart. showed no antinociceptive activity in the mouse writhing test.

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