Patient-reported Outcomes and Their Role in the Assessment of Rheumatoid Arthritis

Overview

Journal Pharmacoeconomics

Specialty Pharmacology

Date 2004 May 26

PMID 15157002

Citations 55

Authors

Deborah P Lubeck

Affiliations

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Abstract

Patients with rheumatoid arthritis (RA) face considerable physical, social and emotional disabilities. In this chronic disease, for which a cure is not yet available, improving patients' health-related quality of life (HRQoL) is of the utmost concern, particularly as the use of long-term and potentially toxic therapy increases. Early HRQoL outcome measures in RA focused on physical functioning, but the social and emotional aspects of the disease are now increasingly important. Thus, several generic and RA-specific HRQoL instruments have been developed, but no one tool covers all areas of HRQoL that affect the patient with RA. For this reason, a combination of generic and disease-specific tools is currently recommended for RA clinical trials.

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References

Leigh J, Fries J, Parikh N . Severity of disability and duration of disease in rheumatoid arthritis. J Rheumatol. 1992; 19(12):1906-11. View

Wolfe F, Cathey M . The assessment and prediction of functional disability in rheumatoid arthritis. J Rheumatol. 1991; 18(9):1298-306. View

Guyatt G, Feeny D, Patrick D . Measuring health-related quality of life. Ann Intern Med. 1993; 118(8):622-9. DOI: 10.7326/0003-4819-118-8-199304150-00009. View

Callahan L, Brooks R, Summey J, Pincus T . Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale. Arthritis Rheum. 1987; 30(6):630-6. DOI: 10.1002/art.1780300605. View

Doyle J . Economic and quality-of-life impact of rheumatoid arthritis. Manag Care. 2001; 10(7 Suppl):15-8. View

Pouchot J, Guillemin F, Coste J, Bregeon C, Sany J . Validity, reliability, and sensitivity to change of a French version of the arthritis impact measurement scales 2 (AIMS2) in patients with rheumatoid arthritis treated with methotrexate. J Rheumatol. 1996; 23(1):52-60. View

Guyatt G, Bombardier C, Tugwell P . Measuring disease-specific quality of life in clinical trials. CMAJ. 1986; 134(8):889-95. PMC: 1490966. View

Kosinski M, Kujawski S, Martin R, Wanke L, Buatti M, Ware Jr J . Health-related quality of life in early rheumatoid arthritis: impact of disease and treatment response. Am J Manag Care. 2002; 8(3):231-40. View

Macran S, Weatherly H, Kind P . Measuring population health: a comparison of three generic health status measures. Med Care. 2003; 41(2):218-31. DOI: 10.1097/01.MLR.0000044901.57067.19. View

10.

Yelin E . Arthritis. The cumulative impact of a common chronic condition. Arthritis Rheum. 1992; 35(5):489-97. View

11.

van Agt H, Essink-Bot M, Krabbe P, Bonsel G . Test-retest reliability of health state valuations collected with the EuroQol questionnaire. Soc Sci Med. 1994; 39(11):1537-44. DOI: 10.1016/0277-9536(94)90005-1. View

12.

Fries J, Spitz P, Young D . The dimensions of health outcomes: the health assessment questionnaire, disability and pain scales. J Rheumatol. 1982; 9(5):789-93. View

13.

Hunt S, McKenna S, McEwen J, Williams J, Papp E . The Nottingham Health Profile: subjective health status and medical consultations. Soc Sci Med A. 1981; 15(3 Pt 1):221-9. DOI: 10.1016/0271-7123(81)90005-5. View

14.

Riemsma R, Rasker J, Taal E, Griep E, Wouters J, Wiegman O . Fatigue in rheumatoid arthritis: the role of self-efficacy and problematic social support. Br J Rheumatol. 1998; 37(10):1042-6. DOI: 10.1093/rheumatology/37.10.1042. View

15.

Harris Jr E . Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med. 1990; 322(18):1277-89. DOI: 10.1056/NEJM199005033221805. View

16.

Katz P, Yelin E . Prevalence and correlates of depressive symptoms among persons with rheumatoid arthritis. J Rheumatol. 1993; 20(5):790-6. View

17.

Liang M, Larson M, Cullen K, Schwartz J . Comparative measurement efficiency and sensitivity of five health status instruments for arthritis research. Arthritis Rheum. 1985; 28(5):542-7. DOI: 10.1002/art.1780280513. View

18.

Gabriel S, Crowson C, Campion M, OFallon W . Indirect and nonmedical costs among people with rheumatoid arthritis and osteoarthritis compared with nonarthritic controls. J Rheumatol. 1997; 24(1):43-8. View

19.

Kopec J, Willison K . A comparative review of four preference-weighted measures of health-related quality of life. J Clin Epidemiol. 2003; 56(4):317-25. DOI: 10.1016/s0895-4356(02)00609-1. View

20.

Patrick D, Deyo R . Generic and disease-specific measures in assessing health status and quality of life. Med Care. 1989; 27(3 Suppl):S217-32. DOI: 10.1097/00005650-198903001-00018. View