Apoptin/VP3 Contains a Concentration-dependent Nuclear Localization Signal (NLS), Not a Tumorigenic Selective NLS

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2004 May 14

PMID 15141008

Citations 9

Authors

J S Wadia

M V Wagner

S A Ezhevsky

S F Dowdy

Affiliations

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Citing Articles

Apoptin as a Tumor-Specific Therapeutic Agent: Current Perspective on Mechanism of Action and Delivery Systems.

Malla W, Arora R, Khan R, Mahajan S, Tiwari A Front Cell Dev Biol. 2020; 8:524.

PMID: 32671070 PMC: 7330108. DOI: 10.3389/fcell.2020.00524.

Enhanced tumour cell nuclear targeting in a tumour progression model.

Nastasie M, Thissen H, Jans D, Wagstaff K BMC Cancer. 2015; 15:76.

PMID: 25885577 PMC: 4342815. DOI: 10.1186/s12885-015-1045-z.

Mechanisms of Apoptin-induced cell death.

Zhou S, Zhang M, Zhang J, Shen H, Tangsakar E, Wang J Med Oncol. 2011; 29(4):2985-91.

PMID: 22105148 DOI: 10.1007/s12032-011-0119-2.

Apoptin nucleocytoplasmic shuttling is required for cell type-specific localization, apoptosis, and recruitment of the anaphase-promoting complex/cyclosome to PML bodies.

Heilman D, Teodoro J, Green M J Virol. 2006; 80(15):7535-45.

PMID: 16840333 PMC: 1563728. DOI: 10.1128/JVI.02741-05.

Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.

Burek M, Maddika S, Burek C, Daniel P, Schulze-Osthoff K, Los M Oncogene. 2005; 25(15):2213-22.

PMID: 16288204 PMC: 2954965. DOI: 10.1038/sj.onc.1209258.

References

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