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Granulocytic Sarcoma in Children

Overview
Journal Neuroradiology
Specialties Neurology
Radiology
Date 2004 Apr 21
PMID 15098141
Citations 6
Authors
L Porto
M Kieslich
D Schwabe
F E Zanella
H Lanfermann
Affiliations
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Abstract

We report three children with leukaemia (two acute myeloid and one acute lymphoblastic) and granulocytic sarcoma in the skull, orbit and sinuses. Lesions in these sites in children, with or without bone changes, are suggestive of systemic diseases such as lymphoproliferative conditions. Although involvement by granulocytic sarcoma, with or without acute myeloid leukaemia, is described, an association with acute lymphoblastic leukaemia is rare. Recognition of this rare entity is important, because early aggressive chemotherapy can bring about regression of the tumour and improve survival.

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